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KMID : 0383820100680030146
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Tuberculosis and Respiratory Diseases
2010 Volume.68 No. 3 p.146 ~ p.154
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The Recent Status of Multidrug- and Extensively Drug-Resistant Tuberculosis in Korea
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Kim Sun-Young
Kim Hee-Jin
Kim Chang-Ki
Yoon Hye-Ryoung
Bae Hye-Gyung
Lee Seon-Hwa
Sung Nack-Moon
Kim Dae-Yeon
Lee Gang-Young
Cho Young-Soo
Lee Sang-Do
Kim Woo-Sung
Kim Dong-Soon
Shim Tae-Sun
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Abstract
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Background: The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has become a serious worldwide problem. However, there is insufficient data regarding the current status of MDR-TB and XDR-TB in Korea. This study examined the recent status of MDR- and XDR-TB using the data from 7 laboratories, in which almost all drug susceptibility tests (DST) for Mycobacterium tuberculosis were performed.
Materials and Methods: The patients’ identification data and DST results were collected from all 7 laboratories from 2001 to 2006 and the number of patients with MDR-TB and XDR-TB were calculated.
Results: The number of DSTs was 140,638 for 6 years with an increasing incidence each year (p＜0.001). The number of DST with MDR results was 18,510 and personal identifying information was obtained in 16,640 (89.9%) tests. The number of MDR-TB patients from 2001 to 2006 was 2,329, 2,496, 2,374, 2,300, 2,354, and 2,178, respectively, when counting the duplications in a year as one patient. The number of MDR-TB patients when counting the duplications in 6 years as one patient was 2,281, 1,977, 1,620, 1,446, 1,512, and 1,373, respectively. When the same method was adopted, the number of XDR-TB patients was 191, 238, 282, 260, 272, and 264, respectively, and 189, 150, 130, 90, 122, and 110 patients, respectively.
Conclusion: Despite the national efforts to control TB, there are still a large number of MDR- and XDR-TB patients in Korea.
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KEYWORD
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Tuberculosis, Multidrug-Resistant, Extensively Drug-Resistant Tuberculosis, Microbial Sensitivity Tests, Korea
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